Description
Anti-dsDNA ELISA Kit
Product Overview:
The Anti-dsDNA ELISA Kit is a highly sensitive diagnostic tool designed for the detection and quantification of anti-double stranded DNA (dsDNA) antibodies in human serum or plasma samples. This kit is ideal for aiding in the diagnosis of autoimmune diseases, particularly Systemic Lupus Erythematosus (SLE), where anti-dsDNA antibodies are commonly elevated.
Key Features:
- High Sensitivity and Specificity: Designed to offer precise results with minimal interference.
- Fast and Easy Procedure: The ELISA format allows for high-throughput testing, enabling quick results within hours.
- Reliable Performance: Proven reliability in detecting anti-dsDNA antibodies, a key biomarker for systemic autoimmune conditions.
- Versatile Applications: Suitable for research and clinical diagnostic laboratories.
- Validated Results: Utilized in both clinical and research settings to monitor disease progression and therapeutic efficacy in patients with autoimmune disorders.
Technical Details:
- Assay Type: Enzyme-Linked Immunosorbent Assay (ELISA)
- Detection Method: Colorimetric detection using a substrate reaction
- Sensitivity: Capable of detecting low concentrations of anti-dsDNA antibodies
- Sample Type: Human serum or plasma
- Storage Conditions: Store at 2-8°C (for up to 12 months)
- Kit Components: Pre-coated microplate, standards, detection antibodies, substrate solution, wash buffer, and stop solution
Applications:
- Diagnostic Testing: Identification and monitoring of anti-dsDNA antibodies in patients suspected of having autoimmune diseases like Systemic Lupus Erythematosus (SLE).
- Research Use: Studying the role of autoantibodies in autoimmune diseases and autoimmune disease pathogenesis.
- Therapeutic Monitoring: Monitoring changes in anti-dsDNA antibody levels during treatment of autoimmune disorders.
Advantages:
- Quantitative Results: Provides exact antibody levels that can be tracked over time.
- Minimal Cross-Reactivity: Designed to specifically detect anti-dsDNA antibodies with minimal cross-reactivity with other autoantibodies.
- Easy-to-Use: Suitable for both experienced researchers and clinicians, with clear instructions and a straightforward protocol.
Precautions:
- For in vitro diagnostic use only.
- Ensure that all reagents are properly stored and handled to maintain the integrity of the assay.
- Follow proper laboratory safety protocols when handling human samples.
Conclusion: The Anti-dsDNA ELISA Kit is an essential tool for diagnosing and monitoring autoimmune diseases, offering precise, reliable, and fast results. It is a critical component in the management of autoimmune disorders, particularly SLE, providing clinicians with important diagnostic information for better patient care.
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